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The principal cytochrome P450 isoenzyme concerned appears to be CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Around 85% of an oral dose appears inside the urine inside of 24 hours of administration, most because the glucuronide conjugate, with smaller amounts of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity details.Stein cla

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